Publications


PubMed NCBI


Selected Publications

Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome. Liang P, Sallam K, Wu H, Li Y, Itzhaki I, Garg P, Zhang Y, Vermglinchan V, Lan F, Gu M, Gong T, Zhuge Y, He C, Ebert AD, Sanchez-Freire V, Churko J, Hu S, Sharma A, Lam CK, Scheinman MM, Bers DM, Wu JC. J Am Coll Cardiol. 2016 Nov 8;68(19):2086-2096

iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy. Kodo K, Ong SG, Jahanbani F, Termglinchan V, Hirono K, InanlooRahatloo K, Ebert AD, Shukla P, Abilez OJ, Churko JM, Karakikes I, Jung G, Ichida F, Wu SM, Snyder MP, Bernstein D, Wu JC. Nat Cell Biol. 2016 Oct;18(10):1031-42

Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity. Burridge PW, Li YF, Matsa E, Wu H, Ong SG, Sharma A, Holmström A, Chang AC, Coronado MJ, Ebert AD, Knowles JW, Telli ML, Witteles RM, Blau HM, Bernstein D, Altman RB, Wu JC. Nat Med. 2016 May;22(5):547-56

Microfluidic Single-Cell Analysis of Transplanted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes After Acute Myocardial Infarction. Ong SG, Huber BC, Lee WH, Kodo K, Ebert AD, Ma Y, Nguyen PK, Diecke S, Chen WY, Wu JC. Circulation. 2015 Aug 25;132(8):762-71.

Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model. Riegler J, Tiburcy M, Ebert A, Tzatzalos E, Raaz U, Abilez OJ, Shen Q, Kooreman NG, Neofytou E, Chen VC, Wang M, Meyer T, Tsao PS, Connolly AJ, Couture LA, Gold JD, Zimmermann WH, Wu JC. Circ Res. 2015 Sep 25;117(8):720-30

Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand? Ebert AD, Diecke S, Chen IY, Wu JC. EMBO Mol Med. 2015 Jul 16;7(9):1090-103. doi: 10.15252/emmm.201504395. Review.

Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system. Ebert AD, Kodo K, Liang P, Wu H, Huber BC, Riegler J, Churko J, Lee J, de Almeida P, Lan F, Diecke S, Burridge PW, Gold JD, Mochly-Rosen D, Wu JC. Sci Transl Med. 2014 Sep 24;6(255):255ra130.

Chemically defined generation of human cardiomyocytes. Burridge PW, Matsa E, Shukla P, Lin ZC, Churko JM, Ebert AD, Lan F, Diecke S, Huber B, Mordwinkin NM, Plews JR, Abilez OJ, Cui B, Gold JD, Wu JC. Nat Methods. 2014 Aug;11(8):855-60

Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. Lan F, Lee AS, Liang P, Sanchez-Freire V, Nguyen PK, Wang L, Han L, Yen M, Wang Y, Sun N, Abilez OJ, Hu S, Ebert AD, Navarrete EG, Simmons CS, Wheeler M, Pruitt B, Lewis R, Yamaguchi Y, Ashley EA, Bers DM, Robbins RC, Longaker MT, Wu JC. Cell Stem Cell. 2013 Jan 3;12(1):101-13

Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns. Sanchez-Freire V, Ebert AD, Kalisky T, Quake SR, Wu JC. Nat Protoc. 2012 Apr 5;7(5):829-38

Induced pluripotent stem cells as a disease modeling and drug screening platform. Ebert AD, Liang P, Wu JC. J Cardiovasc Pharmacol. 2012 Oct;60(4):408-16. doi: 10.1097/FJC.0b013e318247f642. Review.

Tec-kinase-mediated phosphorylation of fibroblast growth factor 2 is essential for unconventional secretion. Ebert AD, Laussmann M, Wegehingel S, Kaderali L, Erfle H, Reichert J, Lechner J, Beer HD, Pepperkok R, Nickel W. Traffic. 2010 Jun;11(6):813-26

A direct role for phosphatidylinositol-4,5-bisphosphate in unconventional secretion of fibroblast growth factor 2. Temmerman K, Ebert AD, Müller HM, Sinning I, Tews I, Nickel W. Traffic. 2008 Jul;9(7):1204-17